Doxycycline shelf life11/11/2023 ![]() ![]() There are no reports of toxicity from degradation products of currently available drugs. When no suitable alternative is available, outdated drugs may be effective, and there is no indication that they are not safe. Renal tubular damage has been reported after use of degraded tetracycline in a formulation that is no longer available (REF 2).” Other sources contain warnings about expired doxycycline, which may (or may not) be based on this outdated tetracycline warning, but patients may want to check with their doctors when using expired doxycycline to be on the safe side. The article also notes the following: “ There are no published reports of human toxicity due to ingestion, injection or topical application of current drug formulations after their expiration date. Notable exceptions include liquid suspensions and epinephrine in Epipen, which are not stable over time. The conclusion of the article indicates that outdated drugs may be effective and safe for at least 5 years after the expiration. The article notes that generally manufacture expiration dates merely reflect the fact that the drug is “stable” at that point, they do not reflect when the drug becomes unstable. A recent article that appeared in the Medical Letter examines the issue in detail. Patients ask all the time about the effectiveness and safety of “expired” drugs. Evidence that chronic disease is caused by pathogens.Transmission of bacteria and onset of chronic disease.Th1 Spectrum Disorder - how chronic inflammatory diseases are related.Successive infection and variability in disease.Therapeutic probe - best method for determining MP suitability.Vitamin D metabolite calculator - get feedback on vitamin D results. ![]()
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